The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin.

The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin.

Hypoxia-inducible factor-1 (HIF) is regulated by oxygen-dependent prolyl hydroxylation. Of the three HIF prolyl hydroxylases (PHD1, 2 and 3) identified, PHD3 exhibits restricted substrate specificity in vitro and is induced in different cell types by diverse stimuli. PHD3 may therefore provide an in...

书目详细资料
Main Authors:	Masson, N, Appelhoff, R, Tuckerman, JR, Tian, Y, Demol, H, Puype, M, Vandekerckhove, J, Ratcliffe, P, Pugh, C
格式:	Journal article
语言:	English
出版:	2004

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