Liver transplantation for acute hepatic failure?
In the absence of definitive medical treatment for severe fulminant hepatic failure, liver transplantation may be appropriate in selected patients. However, uniform and easily applicable criteria for diagnosis of severity and analysis of results are needed to prevent unnecessary transplantation and...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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1990
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| _version_ | 1826291661267795968 |
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| author | Chapman, R Forman, D Peto, R Smallwood, R |
| author_facet | Chapman, R Forman, D Peto, R Smallwood, R |
| author_sort | Chapman, R |
| collection | OXFORD |
| description | In the absence of definitive medical treatment for severe fulminant hepatic failure, liver transplantation may be appropriate in selected patients. However, uniform and easily applicable criteria for diagnosis of severity and analysis of results are needed to prevent unnecessary transplantation and to ensure that patients who may benefit are appropriately treated. Previous regimens for treatment of fulminant hepatic failure were often advocated, on the basis of data from historical controls, for several years until controlled trials failed to show any benefit. To obtain reliable information more rapidly than achieved before, a controlled trial between specialist liver transplant units is needed to establish the role of emergency hepatic transplantation in patients with fulminant hepatic failure. |
| first_indexed | 2024-03-07T03:02:45Z |
| format | Journal article |
| id | oxford-uuid:b18336f8-6b70-47cf-ad67-4e5d75ac7c24 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:02:45Z |
| publishDate | 1990 |
| record_format | dspace |
| spelling | oxford-uuid:b18336f8-6b70-47cf-ad67-4e5d75ac7c242022-03-27T04:04:36ZLiver transplantation for acute hepatic failure?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b18336f8-6b70-47cf-ad67-4e5d75ac7c24EnglishSymplectic Elements at Oxford1990Chapman, RForman, DPeto, RSmallwood, RIn the absence of definitive medical treatment for severe fulminant hepatic failure, liver transplantation may be appropriate in selected patients. However, uniform and easily applicable criteria for diagnosis of severity and analysis of results are needed to prevent unnecessary transplantation and to ensure that patients who may benefit are appropriately treated. Previous regimens for treatment of fulminant hepatic failure were often advocated, on the basis of data from historical controls, for several years until controlled trials failed to show any benefit. To obtain reliable information more rapidly than achieved before, a controlled trial between specialist liver transplant units is needed to establish the role of emergency hepatic transplantation in patients with fulminant hepatic failure. |
| spellingShingle | Chapman, R Forman, D Peto, R Smallwood, R Liver transplantation for acute hepatic failure? |
| title | Liver transplantation for acute hepatic failure? |
| title_full | Liver transplantation for acute hepatic failure? |
| title_fullStr | Liver transplantation for acute hepatic failure? |
| title_full_unstemmed | Liver transplantation for acute hepatic failure? |
| title_short | Liver transplantation for acute hepatic failure? |
| title_sort | liver transplantation for acute hepatic failure |
| work_keys_str_mv | AT chapmanr livertransplantationforacutehepaticfailure AT formand livertransplantationforacutehepaticfailure AT petor livertransplantationforacutehepaticfailure AT smallwoodr livertransplantationforacutehepaticfailure |