Resistance of regulatory T cells to glucocorticoid-induced [corrected] TNFR family-related protein (GITR) during Plasmodium yoelii infection.
CD4+ T cells are the major effector T cells against blood-stage Plasmodium yoelii infection. On the other hand, the lethal strain of P. yoelii (PyL) has acquired an escape mechanism from host T cell immunity by activating CD4+CD25+ regulatory T cells (Treg). Although the activation of Treg during Py...
Main Authors: | Hisaeda, H, Hamano, S, Mitoma-Obata, C, Tetsutani, K, Imai, T, Waldmann, H, Himeno, K, Yasutomo, K |
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Format: | Journal article |
Language: | English |
Published: |
2005
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