Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.

Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.

The structure of the human MHC class I molecule HLA-B53 complexed to two nonameric peptide epitopes (from the malaria parasite P. falciparum and the HIV2 gag protein) has been determined by X-ray crystallography at 2.3 angstrom resolution. The structures reveal the architecture of a Pro-specific B p...

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Bibliographic Details
Main Authors:	Smith, K, Reid, S, Harlos, K, McMichael, A, Stuart, D, Bell, J, Jones, E
Format:	Journal article
Language:	English
Published:	1996

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