Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.

Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.

The structure of the human MHC class I molecule HLA-B53 complexed to two nonameric peptide epitopes (from the malaria parasite P. falciparum and the HIV2 gag protein) has been determined by X-ray crystallography at 2.3 angstrom resolution. The structures reveal the architecture of a Pro-specific B p...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Smith, K, Reid, S, Harlos, K, McMichael, A, Stuart, D, Bell, J, Jones, E
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	1996

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-н: Reid, S, зэрэг
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-н: Hill, A, зэрэг
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-н: Hill, A, зэрэг
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-н: Braud, V, зэрэг
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-н: Nguyen, Thanh Binh, зэрэг
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Maintenance of MHC polymorphism.
-н: Hughes, A, зэрэг
Хэвлэсэн: (1992)

HLA-peptide tetrameric complexes.
-н: Ogg, G, зэрэг
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-н: O'Callaghan, C, зэрэг
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-н: Hoerter, John A. H., зэрэг
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-н: Bridgen, J, зэрэг
Хэвлэсэн: (1976)

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-н: Walters, L, зэрэг
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-н: Cunliffe, S, зэрэг
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-н: Saxena, Shikhar
Хэвлэсэн: (2022)

Tumor defense by murine cytotoxic T cells specific for peptide bound to nonclassical MHC class I.
-н: Griffiths, E, зэрэг
Хэвлэсэн: (1998)

Does increased expression of HLA-C allow better control of HIV-1 viral load?
-н: Brackenridge, S, зэрэг
Хэвлэсэн: (2009)

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-н: Walters, LC, зэрэг
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MHC polymorphisms associated with HIV infection in Uganda
-н: Ali, S, зэрэг
Хэвлэсэн: (1996)

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-н: Kollnberger, S, зэрэг
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Amino acids and peptides /
-н: Jones, J. H.
Хэвлэсэн: (1990)

INTERACTIONS BETWEEN PEPTIDE AND CLASS-I MHC - IMPLICATIONS FOR IMMUNOTHERAPY IN RHEUMATIC DISEASE
-н: Moots, R, зэрэг
Хэвлэсэн: (1993)

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-н: Moots, R, зэрэг
Хэвлэсэн: (1993)

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-н: Held, G, зэрэг
Хэвлэсэн: (2007)

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-н: Li, D, зэрэг
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-н: Hill, A, зэрэг
Хэвлэсэн: (1992)

Recognition surfaces of MHC class I.
-н: Jones, E, зэрэг
Хэвлэсэн: (1998)

Naturally processed HLA class II peptides reveal highly conserved immunogenic flanking region sequence preferences that reflect antigen processing rather than peptide-MHC interactions.
-н: Godkin, A, зэрэг
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-н: Bowness, P, зэрэг
Хэвлэсэн: (1993)

TCR binding to peptide-MHC stabilizes a flexible recognition interface.
-н: Willcox, B, зэрэг
Хэвлэсэн: (1999)

Evidence of widespread binding of HLA class I molecules to peptides.
-н: Frelinger, J, зэрэг
Хэвлэсэн: (1990)