A Cerberus-Nodal-Lefty-Pitx signalling cascade controls Left-Right asymmetry in amphioxus

Many bilaterally symmetrical animals develop genetically-programmed left-right asymmetries. In vertebrates this process is under the control of Nodal signalling, which is restricted to the left side of the body by the Nodal antagonists Cerberus and Lefty. Amphioxus, the earliest diverging chordate l...

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Detalhes bibliográficos
Principais autores: Li, G, Liu, X, Xing, C, Zhang, H, Shimeld, S, Wang, Y
Formato: Journal article
Publicado em: National Academy of Sciences 2017