Physicochemical and biological evaluation of siRNA polyplexes based on PEGylated Poly(amido amine)s.

Physicochemical and biological evaluation of siRNA polyplexes based on PEGylated Poly(amido amine)s.

PURPOSE: Use of RNA interference as novel therapeutic strategy is hampered by inefficient delivery of its mediator, siRNA, to target cells. Cationic polymers have been thoroughly investigated for this purpose but often display unfavorable characteristics for systemic administration, such as interac...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Vader, P, van der Aa, L, Engbersen, J, Storm, G, Schiffelers, R
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2012

समान संसाधन

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