Induction of T helper type 1 and 2 responses to 19-kilodalton merozoite surface protein 1 in vaccinated healthy volunteers and adults naturally exposed to malaria.

Plasmodium falciparum malaria is a major cause of death in the tropics. The 19-kDa subunit of P. falciparum merozoite surface protein 1 (MSP-1(19)), a major blood stage vaccine candidate, is the target of cellular and humoral immune responses in animals and humans. In this phase I trial of MSP-1(19)...

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Hlavní autoři: Lee, E, Palmer, DR, Flanagan, K, Reece, W, Odhiambo, K, Marsh, K, Pinder, M, Gravenor, M, Keitel, W, Kester, K, Diggs, C, Kaslow, D, Apostolopoulos, V, Ballou, W, Hill, A, Krzych, U, Plebanski, M
Médium: Journal article
Jazyk:English
Vydáno: 2002