Substitution of the R1 hydroxyl and C1 phosphate of risedronate produces differences in elution profiles on hydroxyapatite ceramic chromatographic columns

Substitution of the R1 hydroxyl and C1 phosphate of risedronate produces differences in elution profiles on hydroxyapatite ceramic chromatographic columns

Bibliographic Details
Main Authors:	Xia, Z, Lawson, M, Triffitt, J, Ebetino, F, McKenna, C, Marina, M, Kashimirov, B, Russell, R
Format:	Conference item
Published:	2006

Similar Items

Substitutions in the R1 hydroxyl and C1 phosphate positions significantly affect binding of risedronate during hydroxyapatite ceramic chromatography
by: Xia, Z, et al.
Published: (2006)

A novel method to characterize relative mineral binding affinities of bisphosphonates and the structural requirements for binding by using ceramic hydroxyapatite column chromatography.
by: Xia, Z, et al.
Published: (2006)

Differences in the potential binding of phosphate containing compounds to bone mineral are revealed by the novel use of hydroxyapatite column chromatography
by: Lawson, M, et al.
Published: (2005)

Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate.
by: Marma, MS, et al.
Published: (2007)

Refining the use of hydroxyapatite column chromatography to reveal differences in relative binding affinities of bisphosphonates
by: Lawson, M, et al.
Published: (2006)

The use of hydroxyapatite column chromatography as a novel method to reveal differences in relative binding affinities of bisphosphonates
by: Lawson, M, et al.
Published: (2005)

Fluorescently labeled risedronate and related analogues: "magic linker" synthesis.
by: Kashemirov, B, et al.
Published: (2008)

Potential bone mineral binding differences among bisphosphonates can be demonstrated by the use of hydroxyapatite column chromatography.
by: Lawson, M, et al.
Published: (2005)

Fluorescently labeled risedronate and related analogs: Design and evaluation as imaging probes
by: Coxon, F, et al.
Published: (2008)

Fluorescently labeled risedronate and related analocs: Design and evaluation as imaging probes
by: Coxon, F, et al.
Published: (2008)

Studies to elucidate the anti-tumor mechanism of action of risedronate in human myeloma cells; Use of an analogue of risedronate reveals the effects of differential inhibition of prenylation
by: Roelofs, A, et al.
Published: (2005)

Predicting pharmacological potencies of nitrogen-containing bisphosphonates; novel methods dissociate enzyme- and hydroxyapatite-binding affinities
by: Xia, Z, et al.
Published: (2007)

Evaluation of the relative mineral-binding affinities of clinically-relevant bisphosphonates by hydroxyapatite-column chromatography
by: Xia, Z, et al.
Published: (2008)

NE10790, a phosphonocarboxylate analogue of risedronate, induces human myeloma cell apoptosis in vitro
by: Roelofs, A, et al.
Published: (2004)

Prolonged osteogenesis from human mesenchymal stem cells implanted in immunodeficient mice by using coralline hydroxyapatite incorporating rhBMP2 microspheres.
by: Fu, K, et al.
Published: (2010)

The ROSI study (risedronate in adults with osteogenesis imperfecta type 1)
by: Duncan, E, et al.
Published: (2005)

Role of the geminal hydroxyl group in target enzyme inhibition by bisphosphonates and phosphonocarboxylates
by: Stewart, C, et al.
Published: (2007)

Separation of Chromatographic Co-Eluted Compounds by Clustering and by Functional Data Analysis
by: Aneta Sawikowska, et al.
Published: (2021-03-01)

Alendronate and ibandronate affect osteoclast formation and size differently from risedronate and zoledronate
by: Mabilleau, G, et al.
Published: (2011)

Differences between bisphosphonates in binding affinities for hydroxyapatite.
by: Lawson, M, et al.
Published: (2010)

Predicting the clinical potencies of bisphosphonates: Divergence of hydroxyapatite and farnesyl diphosphate synthase binding affinities
by: Xia, Z, et al.
Published: (2007)

Crystal structures and molecular interactions of risedronate and zoledronate with human farnesyl diphosphate synthase
by: Kavanagh, K, et al.
Published: (2006)

Effects of Risedronate and alendronate on colonic inflammation and bone loss in a mouse model of acute colitis
by: Brounais-Le Royer, B, et al.
Published: (2012)

Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice
by: Hiroko Okawa, et al.
Published: (2022-09-01)

Determination of the relative bone mineral-binding affinities of bisphosphonates by using hydroxyapatite-column chromatography combined with mass spectrometric analysis
by: Duan, X, et al.
Published: (2010)

Column types for the chromatographic analysis of oleochemicals /
by: Ottenstein, D. M.

Evaluation of the relative mineral-binding affinities of clinically-relevant bisphosphonates by using hydroxyapatite-column chromatography and adsorption isotherms combined with mass spectrometric analysis
by: Xia, Z, et al.
Published: (2008)

Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in mice.
by: Sugiyama, T, et al.
Published: (2011)

BBD Driven Fabrication of Hydroxyapatite Engineered Risedronate Loaded Thiolated Chitosan Nanoparticles and Their In Silico, In Vitro, and Ex Vivo Studies
by: Zoya Saifi, et al.
Published: (2023-11-01)

Quantitative Structure–Retention Relationships with Non-Linear Programming for Prediction of Chromatographic Elution Order
by: J. Jay Liu, et al.
Published: (2019-07-01)

Nitrogen-containing bisphosphonates and prediction of their clinical potencies: Dissociation of target enzyme- and hydroxyapatite-binding affinities
by: Xia, Z, et al.
Published: (2007)

Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells.
by: Roelofs, A, et al.
Published: (2006)

Gradient elution in column liquid chromatography : theory and practice/
by: 403061 Jandera, P., et al.
Published: (1985)

Efficacy of topical risedronate and risedronate - Eudragit E complex in a model of cutaneous leishmaniasis induced by Leishmania (Leishmania) amazonensis
by: Ma. Florencia Peralta, et al.
Published: (2021-05-01)

Bioactivity Evaluation of Biphasic Hydroxyapatite Bone Substitutes Immersed and Grown with Supersaturated Calcium Phosphate Solution
by: Yusuke Yamaguchi, et al.
Published: (2021-09-01)

Risedronate-loaded aerogel scaffolds for bone regeneration
by: Nahla El-Wakil, et al.
Published: (2023-12-01)

Phos-tag-based phosphate affinity chromatographic techniques
by: Emiko Kinoshita-Kikuta, et al.
Published: (2022-11-01)

An open‐label randomized study of the relative absorption of gastro‐resistant risedronate taken fasted or with food versus immediate‐release risedronate
by: Diane Kleinermans, et al.
Published: (2022-06-01)

In-Line Vis-NIR Spectral Analysis for the Column Chromatographic Processes of the <i>Ginkgo biloba</i> L. Leaves. Part II: Batch-to-Batch Consistency Evaluation of the Elution Process
by: Wenlong Li, et al.
Published: (2022-11-01)

Composites based on calcium phosphate foam ceramic and hydroxyapatite gel
by: V.K. Krut’ko, et al.
Published: (2022-12-01)