Substitution of the R1 hydroxyl and C1 phosphate of risedronate produces differences in elution profiles on hydroxyapatite ceramic chromatographic columns

Geahča maid

• Substitutions in the R1 hydroxyl and C1 phosphate positions significantly affect binding of risedronate during hydroxyapatite ceramic chromatography
  Dahkki: Xia, Z, et al.
  Almmustuhtton: (2006)
• A novel method to characterize relative mineral binding affinities of bisphosphonates and the structural requirements for binding by using ceramic hydroxyapatite column chromatography.
  Dahkki: Xia, Z, et al.
  Almmustuhtton: (2006)
• Differences in the potential binding of phosphate containing compounds to bone mineral are revealed by the novel use of hydroxyapatite column chromatography
  Dahkki: Lawson, M, et al.
  Almmustuhtton: (2005)
• Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate.
  Dahkki: Marma, MS, et al.
  Almmustuhtton: (2007)
• Refining the use of hydroxyapatite column chromatography to reveal differences in relative binding affinities of bisphosphonates
  Dahkki: Lawson, M, et al.
  Almmustuhtton: (2006)