Synthesis and mechanistic analyses of boron-containing β-lactamase inhibitors

<p>The work described in this thesis focused on exploration of the versatile chemistry of boron to access functionalised bicyclic and acyclic boron-containing structures for use as enzyme inhibitors. Cyclic boronic acids/esters are emerging as promising scaffolds for broad-spectrum inhibition...

Полное описание

Библиографические подробности
Главный автор: Krajnc, A
Другие авторы: Schofield, C
Формат: Диссертация
Язык:English
Опубликовано: 2020
Предметы: