The Mendelian colorectal cancer syndromes

A small minority of colorectal cancers (CRCs) (≤5%) are caused by a single, inherited faulty gene. These diseases, the Mendelian colorectal cancer (CRC) syndromes, have been central to our understanding of colorectal carcinogenesis in general. Most of the approximately 13 high-penetrance genes that...

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Bibliographic Details
Main Author: Tomlinson, I
Format: Journal article
Language:English
Published: SAGE Publications 2015