Increased asymmetric dimethylarginine in severe falciparum malaria: Association with impaired nitric oxide bioavailability and fatal outcome

Increased asymmetric dimethylarginine in severe falciparum malaria: Association with impaired nitric oxide bioavailability and fatal outcome

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Asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase (NOS), is a predictor of mortality in critical illness. Severe malaria (SM) is associated with decreased NO bioavailability, but the contribution of ADMA to the pathogenesis of impaired NO bioavailability and adve...

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Main Authors: Yeo, T, Lampah, D, Tjitra, E, Gitawati, R, Darcy, C, Jones, C, Kenangalem, E, McNeil, Y, Granger, D, Lopansri, B, Weinberg, J, Price, R, Duffull, S, Celermajer, D, Anstey, N
格式: Journal article
語言:English
出版: Public Library of Science 2010

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