A quantitative analysis of cardiac myocyte relaxation: a simulation study

The determinants of relaxation in cardiac muscle are poorly understood, yet compromised relaxation accompanies various pathologies and impaired pump function. In this study, we develop a model of active contraction to elucidate the relative importance of the [Ca2+]i transient magnitude, the unbindin...

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Bibliographic Details
Main Authors: Niederer, S, Hunter, P, Smith, N
Format: Journal article
Published: 2006