Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles.

Extracellular vesicles (EVs) are specialised endogenous carriers of proteins and nucleic acids and are involved in intercellular communication. EVs are therefore proposed as candidate drug delivery systems for the delivery of nucleic acids and other macromolecules. However, the preparation of EV-bas...

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Main Authors: Kooijmans, SA, Stremersch, S, Braeckmans, K, de Smedt, S, Hendrix, A, Wood, M, Schiffelers, R, Raemdonck, K, Vader, P
格式: Journal article
语言:English
出版: 2013