Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology

Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology

Human induced pluripotent stem cell derived cardiomyocytes (iPSC-CMs) have applications in disease modeling, cell therapy, drug screening and personalized medicine. Computational models can be used to interpret experimental findings in iPSC-CMs, provide mechanistic insights, and translate these find...

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Bibliographic Details
Main Authors:	Lei, C, Wang, K, Clerx, M, Johnstone, R, Hortigon-Vinagre, M, Zamora, V, Allan, A, Smith, G, Gavaghan, D, Mirams, G, Polonchuk, L
Format:	Journal article
Published:	Frontiers Media 2017

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