A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment.

A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment.

Show other versions (1)

Prophylactic vaccination against HIV-1 sexual transmission will probably require antibody elicitation at genital mucosal surfaces. However, HIV-1 envelope glycoprotein (Env)-based antigens are weakly immunogenic, particularly when applied mucosally. The polyanion PRO 2000 is safe for human vaginal a...

Full description

Bibliographic Details
Main Authors:	Wegmann, F, Krashias, G, Lühn, K, Laamanen, K, Vieira, S, Jeffs, SA, Shattock, R, Sattentau, Q
Format:	Journal article
Language:	English
Published:	2011

Similar Items

A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment
by: Wegmann, F, et al.
Published: (2011)

Immunogenicity of HIV-1 gp140 - microbicide mixtures in mice using a vaginal delivery model
by: Wegmann, F, et al.
Published: (2007)

Polyethyleneimine Is a Potent Mucosal Adjuvant and Candidate Adjuvant for HIV-1 Vaccination
by: Brinckmann, S, et al.
Published: (2011)

Carnauba wax nanoparticles enhance strong systemic and mucosal cellular and humoral immune responses to HIV-gp140 antigen.
by: Arias, M, et al.
Published: (2011)

Mucosally-targeted HIV-1 vaccines.
by: Wegmann, F
Published: (2011)

Production and characterization of high-affinity human monoclonal antibodies to human immunodeficiency virus type 1 envelope glycoproteins in a mouse model expressing human immunoglobulins.
by: Sheppard, N, et al.
Published: (2007)

Mucosal immunology and models of mucosal HIV infection
by: GE Griffin, et al.
Published: (1996-06-01)

Neutralization of HIV-1 by antibody.
by: Sattentau, Q
Published: (1996)

Assessment of mucosal immunity to HIV-1.
by: Jespers, V, et al.
Published: (2010)

Human monoclonal antibodies to HIV-1 gp140 from mice bearing YAC-based human immunoglobulin transloci.
by: Pruzina, S, et al.
Published: (2011)

Human monoclonal antibodies to HIV-1 gp140 from mice bearing YAC-based human immunoglobulin transloci
by: Pruzina, S, et al.
Published: (2011)

Correlates of antibody-mediated protection against HIV infection.
by: Sattentau, Q
Published: (2008)

Degradable PEI Form as Safer Alternative for HIV-1 Vaccine Development and Adjuvant Potency as a Common Trait of Oligoethyleneimines
by: Brinckmann, S, et al.
Published: (2011)

Limitations of the anti-idiotype strategy for an HIV vaccine.
by: Beverley, P, et al.
Published: (1989)

Antibody neutralization of HIV-1.
by: Poignard, P, et al.
Published: (1996)

Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens.
by: Wegmann, F, et al.
Published: (2012)

HIV-gp140 Antigen-Adsorbed Wax Nanoparticles Induce Strong In Vivo Systemic and Mucosal Humoral Immune Responses
by: Arias, M, et al.
Published: (2008)

HIV-1 antibody--debris or virion?
by: Parren, P, et al.
Published: (1997)

Potent adaptive immune responses induced against HIV-1 gp140 and influenza virus HA by a polyanionic carbomer.
by: Krashias, G, et al.
Published: (2010)

Antigenicity and Immunogenicity in HIV-1 Antibody-Based Vaccine Design.
by: Kong, L, et al.
Published: (2012)

New templates for HIV-1 antibody-based vaccine design
by: Sattentau, Q, et al.
Published: (2010)

Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens.
by: Sheppard, N, et al.
Published: (2014)

Cell-to-cell spread of HIV-1 and evasion of neutralizing antibodies.
by: Schiffner, T, et al.
Published: (2013)

New templates for HIV-1 antibody-based vaccine design.
by: Sattentau, Q, et al.
Published: (2010)

Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity.
by: Kong, L, et al.
Published: (2010)

Expression-System-Dependent Modulation of HIV-1 Envelope Glycoprotein Antigenicity and Immunogenicity
by: Kong, L, et al.
Published: (2010)

Sterile inflammation induced by Carbopol elicits robust adaptive immune responses in the absence of pathogen-associated molecular patterns
by: Gartlan, K, et al.
Published: (2016)

Rate and predictors of mucosal healing in patients with inflammatory bowel disease treated with anti-TNF-alpha antibodies.
by: Florian Beigel, et al.
Published: (2014-01-01)

HIV-1 antibody - Debris or virion? (vol 3, pg 366, 1997)
by: Parren, P, et al.
Published: (1997)

Monoclonal antibodies to HIV-1 gp120: a request.
by: Moore, J, et al.
Published: (1993)

Expression and characterisation of recombinant oligomeric envelope glycoproteins derived from primary isolates of HIV-1.
by: Jeffs, SA, et al.
Published: (2004)

Meta-analysis of HIV-1 vaccine elicited mucosal antibodies in humans
by: Kelly E. Seaton, et al.
Published: (2021-04-01)

HIV-Specific Antibodies Mediate Rapid Antibody-Dependent Cellular Cytotoxicity Against Primary HIV-Infected CD4+T Cells
by: Smalls-Mantey, A, et al.
Published: (2010)

Anti-HIV IgA isotypes: differential virion capture and inhibition of transcytosis are linked to prevention of mucosal R5 SHIV transmission.
by: Watkins, J, et al.
Published: (2013)

Failure to demonstrate anti-lymphocytic antibody in serum of patients with AIDS.
by: Beall, G, et al.
Published: (1987)

Antibody-based HIV-1 vaccines: recent developments and future directions.
by: Montefiori, D, et al.
Published: (2007)

Antibody-based HIV-1 vaccines: recent developments and future directions
by: Montefiori, D, et al.
Published: (2007)

The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity.
by: Parren, P, et al.
Published: (1999)

HIV's gut feeling.
by: Sattentau, Q
Published: (2008)

HIV gp120: double lock strategy foils host defences.
by: Sattentau, Q
Published: (1998)