Iminosugars counteract the downregulation of the interferon gamma receptor by dengue virus

Iminosugars counteract the downregulation of the interferon gamma receptor by dengue virus

The antiviral mechanism of action of iminosugars against many enveloped viruses is hypothesized to be a consequence of misfolding of viral N-linked glycoproteins through inhibition of host endoplasmic reticulum alpha-glucosidase enzymes. Iminosugar treatment of dengue virus (DENV) infection results...

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Những tác giả chính:	Miller, J, Hill, M, Brun, J, Pountain, A, Sayce, A, Zitzmann, N
Định dạng:	Journal article
Được phát hành:	Elsevier 2019

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