Iminosugars counteract the downregulation of the interferon gamma receptor by dengue virus
The antiviral mechanism of action of iminosugars against many enveloped viruses is hypothesized to be a consequence of misfolding of viral N-linked glycoproteins through inhibition of host endoplasmic reticulum alpha-glucosidase enzymes. Iminosugar treatment of dengue virus (DENV) infection results...
Main Authors: | Miller, J, Hill, M, Brun, J, Pountain, A, Sayce, A, Zitzmann, N |
---|---|
格式: | Journal article |
出版: |
Elsevier
2019
|
相似书籍
-
Liposome-mediated delivery of iminosugars enhances efficacy against dengue virus in vivo.
由: Miller, J, et al.
出版: (2012) -
Mechanisms of antiviral activity of iminosugars against dengue virus
由: Miller, JL, et al.
出版: (2018) -
Iminosugars as dengue virus therapeutics: Molecular mechanisms of action of a drug entering clinical trials
由: Sayce, A, et al.
出版: (2014) -
Iminosugars: promising therapeutics for influenza infection
由: Tyrrell, B, et al.
出版: (2016) -
Antiviral effects of deoxynojirimycin (DNJ)-based iminosugars in dengue virus-infected primary dendritic cells
由: Perera, N, et al.
出版: (2022)