Iminosugars counteract the downregulation of the interferon gamma receptor by dengue virus

The antiviral mechanism of action of iminosugars against many enveloped viruses is hypothesized to be a consequence of misfolding of viral N-linked glycoproteins through inhibition of host endoplasmic reticulum alpha-glucosidase enzymes. Iminosugar treatment of dengue virus (DENV) infection results...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Miller, J, Hill, M, Brun, J, Pountain, A, Sayce, A, Zitzmann, N
Fformat: Journal article
Cyhoeddwyd: Elsevier 2019