Iminosugars counteract the downregulation of the interferon gamma receptor by dengue virus

The antiviral mechanism of action of iminosugars against many enveloped viruses is hypothesized to be a consequence of misfolding of viral N-linked glycoproteins through inhibition of host endoplasmic reticulum alpha-glucosidase enzymes. Iminosugar treatment of dengue virus (DENV) infection results...

Повний опис

Бібліографічні деталі
Автори: Miller, J, Hill, M, Brun, J, Pountain, A, Sayce, A, Zitzmann, N
Формат: Journal article
Опубліковано: Elsevier 2019