Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues.

Many mechanisms have been proposed to explain why immune responses against human tumor antigens are generally ineffective. For example, tumor cells have been shown to develop active immune evasion mechanisms. Another possibility is that tumor antigens are unable to optimally stimulate tumor-specific...

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Autors principals: Valmori, D, Fonteneau, J, Valitutti, S, Gervois, N, Dunbar, R, Liénard, D, Rimoldi, D, Cerundolo, V, Jotereau, F, Cerottini, J, Speiser, D, Romero, P
Format: Journal article
Idioma:English
Publicat: 1999