Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.

To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult waist circumference (WC) and waist-hip ratio (WHR). We selected 26 SNPs for follow-up, for which the evidence of asso...

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Autors principals: Lindgren, C, Heid, I, Randall, J, Lamina, C, Steinthorsdottir, V, Qi, L, Speliotes, E, Thorleifsson, G, Willer, C, Herrera, B, Jackson, A, Lim, N, Scheet, P, Soranzo, N, Amin, N, Aulchenko, Y, Chambers, J, Drong, A, Luan, J, Lyon, H, Rivadeneira, F, Sanna, S, Timpson, N, Zillikens, M, Zhao, J
Format: Journal article
Idioma:English
Publicat: 2009
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Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution per Lindgren, C, Heid, I, Randall, J, Lamina, C, Steinthorsdottir, V, Qi, L, Speliotes, E, Thorleifsson, G, Willer, C, Herrera, B, Jackson, A, Lim, N, Scheet, P, Soranzo, N, Amin, N, Aulchenko, Y, Chambers, J, Drong, A, Luan, J, Lyon, H, Rivadeneira, F, Sanna, S, Timpson, N, Zillikens, M, Zhao, J, Almgren, P, Bandinelli, S, Bennett, A, Bergman, R, Bonnycastle, L, Bumpstead, S, Chanock, S, Cherkas, L, Chines, P, Coin, L, Cooper, C, Crawford, G, Doering, A, Dominiczak, A, Doney, A, Ebrahim, S, Elliott, P, Erdos, MR, Estrada, K, Ferrucci, L, Fischer, G, Forouhi, N, Gieger, C, Grallert, H, Groves, C, Grundy, S, Guiducci, C, Hadley, D, Hamsten, A, Havulinna, A, Hofman, A, Holle, R, Holloway, J, Illig, T, Isomaa, B, Jacobs, L, Jameson, K, Jousilahti, P, Karpe, F, Kuusisto, J, Laitinen, J, Lathrop, G, Lawlor, D, Mangino, M, McArdle, W, Meitinger, T, Morken, M, Morris, A, Munroe, P, Narisu, N, Nordstrom, A, Nordstrom, P, Oostra, B, Palmer, C, Payne, F, Peden, J, Prokopenko, I, Renstrom, F, Ruokonen, A, Salomaa, V, Sandhu, MS, Scott, L, Scuteri, A, Silander, K, Song, K, Yuan, X, Stringham, H, Swift, A, Tuomi, T, Uda, M, Vollenweider, P, Waeber, G, Wallace, C, Walters, G, Weedon, M, Witteman, J, Zhang, C, Zhang, W, Caulfield, M, Collins, F, Smith, G, Day, I, Franks, P, Hattersley, A, Hu, F, Jarvelin, MR, Kong, A, Kooner, J, Laakso, M, Lakatta, E, Mooser, V, Morris, A, Peltonen, L, Samani, N, Spector, T, Strachan, D, Tanaka, T, Tuomilehto, J, Uitterlinden, A, van Duijn, C, Wareham, N, Waterworth, D, Boehnke, M, Deloukas, P, Groop, L, Hunter, D, Thorsteinsdottir, U, Schlessinger, D, Wichmann, H, Frayling, T, Abecasis, G, Hirschhorn, J, Loos, R, Stefansson, K, Mohlke, K, Barroso, I, McCarthy, M, Cons, W, Consortia, HWPROCARDIS, Consortium, GIANT, Davey Smith, G, Watkins For The Procardis Consortia, H, McCarthy For The Giant Consortium, MI

Publicat 2010
Journal article