2010 Young Investigator Award winner: Therapeutic aprotinin stimulates osteoblast proliferation but inhibits differentiation and bone matrix mineralization.

2010 Young Investigator Award winner: Therapeutic aprotinin stimulates osteoblast proliferation but inhibits differentiation and bone matrix mineralization.

STUDY DESIGN: Analysis of the effect of antifibrinolytics on in vitro bone formation. OBJECTIVE: As the direct effect of antifibrinolytics on bone formation is unknown, we examined whether antifibrinolytics routinely used in spine surgery, namely, aprotinin and aminocaproic acid, affect osteoblast...

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Bibliographic Details
Main Authors: Schoenecker, J, Mignemi, N, Stutz, C, Liu, Q, Edwards, J, Lynch, C, Holt, G, Schwartz, H, Mencio, G, Hamm, H
Format: Journal article
Language:English
Published: 2010

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