Disassembly of intact multiprotein complexes in the gas phase.
The observation of multiprotein complexes by mass spectrometry formerly relied upon chemical cross-linking to maintain interactions. Recent technological developments have enabled the observation of intact macromolecular complexes without modification. These assemblies, with masses far in excess of...
| Asıl Yazarlar: | , |
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| Materyal Türü: | Journal article |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
1999
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| _version_ | 1826291913866608640 |
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| author | Rostom, A Robinson, C |
| author_facet | Rostom, A Robinson, C |
| author_sort | Rostom, A |
| collection | OXFORD |
| description | The observation of multiprotein complexes by mass spectrometry formerly relied upon chemical cross-linking to maintain interactions. Recent technological developments have enabled the observation of intact macromolecular complexes without modification. These assemblies, with masses far in excess of those measured previously, can be examined through controlled dissociation in the mass spectrometer, revealing information about their subunit interactions and topology. |
| first_indexed | 2024-03-07T03:06:38Z |
| format | Journal article |
| id | oxford-uuid:b2c5d0c1-1e1f-49f3-ab6d-8f1a2e7e1df4 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:06:38Z |
| publishDate | 1999 |
| record_format | dspace |
| spelling | oxford-uuid:b2c5d0c1-1e1f-49f3-ab6d-8f1a2e7e1df42022-03-27T04:14:02ZDisassembly of intact multiprotein complexes in the gas phase.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b2c5d0c1-1e1f-49f3-ab6d-8f1a2e7e1df4EnglishSymplectic Elements at Oxford1999Rostom, ARobinson, CThe observation of multiprotein complexes by mass spectrometry formerly relied upon chemical cross-linking to maintain interactions. Recent technological developments have enabled the observation of intact macromolecular complexes without modification. These assemblies, with masses far in excess of those measured previously, can be examined through controlled dissociation in the mass spectrometer, revealing information about their subunit interactions and topology. |
| spellingShingle | Rostom, A Robinson, C Disassembly of intact multiprotein complexes in the gas phase. |
| title | Disassembly of intact multiprotein complexes in the gas phase. |
| title_full | Disassembly of intact multiprotein complexes in the gas phase. |
| title_fullStr | Disassembly of intact multiprotein complexes in the gas phase. |
| title_full_unstemmed | Disassembly of intact multiprotein complexes in the gas phase. |
| title_short | Disassembly of intact multiprotein complexes in the gas phase. |
| title_sort | disassembly of intact multiprotein complexes in the gas phase |
| work_keys_str_mv | AT rostoma disassemblyofintactmultiproteincomplexesinthegasphase AT robinsonc disassemblyofintactmultiproteincomplexesinthegasphase |