Endothelial-smooth muscle cell interactions in the regulation of vascular tone in skeletal muscle.
The smooth muscle cells (SMCs) of skeletal muscle arterioles are intricately sensitive to changes in membrane potential. Upon increasing luminal pressure, the SMCs depolarize, thereby opening voltage-dependent Ca(2+) channels (VDCCs), which leads to contraction. Mechanisms that oppose this myogenic...
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| Format: | Journal article |
| Language: | English |
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Wiley
2016
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