Molecular basis of MHC I quality control in the peptide loading complex.

Major histocompatibility complex class I (MHC I) molecules are central to adaptive immunity. Their assembly, epitope selection, and antigen presentation are controlled by the MHC I glycan through a sophisticated network of chaperones and modifying enzymes. However, the mechanistic integration of the...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Domnick, A, Winter, C, Sušac, L, Hennecke, L, Hensen, M, Zitzmann, N, Trowitzsch, S, Thomas, C, Tampé, R
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: Springer Nature 2022