Molecular basis of MHC I quality control in the peptide loading complex.

Major histocompatibility complex class I (MHC I) molecules are central to adaptive immunity. Their assembly, epitope selection, and antigen presentation are controlled by the MHC I glycan through a sophisticated network of chaperones and modifying enzymes. However, the mechanistic integration of the...

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Bibliografski detalji
Glavni autori: Domnick, A, Winter, C, Sušac, L, Hennecke, L, Hensen, M, Zitzmann, N, Trowitzsch, S, Thomas, C, Tampé, R
Format: Journal article
Jezik:English
Izdano: Springer Nature 2022