Structure and dynamics of triazole-linked DNA: biocompatibility explained.
Blending in: A triazole-modified DNA duplex is perturbed in structure and dynamics, but this is delocalized over five base pairs. The conformation remains B-DNA and hydrogen bonds between the DNA phosphate oxygen and polymerases can be mimicked by the triazole nitrogen (see figure). The results expl...
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Bibliographic Details
Main Authors: |
Dallmann, A,
El-Sagheer, A,
Dehmel, L,
Mügge, C,
Griesinger, C,
Ernsting, N,
Brown, T |
Format: | Journal article
|
Language: | English |
Published: |
2011
|