Effective antigen presentation by dendritic cells is NF-kappaB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines.

Antigen presentation is a key rate-limiting step in the immune response. Dendritic cells (DC) are the most potent antigen-presenting cells for naive T cells, due to their high expression of MHC and co-stimulatory molecules, but little is known about the biochemical pathways that regulate this functi...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Yoshimura, S, Bondeson, J, Foxwell, B, Brennan, F, Feldmann, M
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2001