Ectopic Tbx2 expression results in polyploidy and cisplatin resistance.

T-box factors play critical roles in embryonic development and have been implicated in cell cycle regulation and cancer. For example, Tbx2 can suppress senescence through a mechanism involving the repression of the cyclin-dependent kinase inhibitors, p19(ARF) and p21(WAF1/CIP1/SDII), and the Tbx2 ge...

Повний опис

Бібліографічні деталі
Автори: Davis, E, Teng, H, Bilican, B, Parker, M, Liu, B, Carriera, S, Goding, C, Prince, S
Формат: Journal article
Мова:English
Опубліковано: 2008

Схожі ресурси