A touching case of channel regulation: the ATP-sensitive K+ channel.
The classical type of KATP channel is an octameric (4:4) complex of two structurally unrelated subunits, Kir6.2 and SUR. The former serves as an ATP-inhibitable pore, while SUR is a regulatory subunit endowing sensitivity to sulphonylurea and K+ channel opener drugs, and the potentiatory action of M...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1998
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