A touching case of channel regulation: the ATP-sensitive K+ channel.

The classical type of KATP channel is an octameric (4:4) complex of two structurally unrelated subunits, Kir6.2 and SUR. The former serves as an ATP-inhibitable pore, while SUR is a regulatory subunit endowing sensitivity to sulphonylurea and K+ channel opener drugs, and the potentiatory action of M...

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Príomhchruthaitheoirí: Tucker, S, Ashcroft, F
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 1998