Structure and chromosomal location of the mouse interleukin-12 p35 and p40 subunit genes.

Interleukin-12 (IL-12) is a heterodimeric cytokine composed of p35 and p40 subunits and is required for induction of T helper 1 (Th1) responses. Knowledge of how the IL-12 gene is regulated will permit an understanding of susceptibility and resistance to pathogenic microbes and to autoiummune diseas...

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Hlavní autoři: Tone, Y, Thompson, SA, Babik, J, Nolan, K, Tone, M, Raven, C, Waldmann, H
Médium: Journal article
Jazyk:English
Vydáno: 1996