Ascertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi

Typhoid fever is endemic across sub-Saharan Africa. However, estimates of the burden of typhoid are undermined by insufficient blood volumes and lack of sensitivity of blood culture. Here, we aimed to address this limitation by exploiting pre-enrichment culture followed by PCR, alongside routine blo...

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Main Authors: Msefula, CL, Olgemoeller, F, Jambo, N, Segula, D, Van Tan, T, Nyirenda, TS, Nedi, W, Kennedy, N, Graham, M, Henrion, MYR, Baker, S, Feasey, N, Gordon, M, Heyderman, RS
格式: Journal article
语言:English
出版: Public Library of Science 2019