Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria

Transcription in bacteria is controlled by multiple molecular mechanisms that precisely regulate gene expression. It has been recently shown that initial RNA synthesis by the bacterial RNA polymerase (RNAP) is interrupted by pauses; however, the pausing determinants and the relationship of pausing w...

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Bibliografiske detaljer
Main Authors:	Dulin, D, Bauer, D, Malinen, A, Bakermans, J, Kaller, M, Morichaud, Z, Petushkov, I, Depken, M, Brodolin, K, Kulbachinskiy, A, Kapanidis, A
Format:	Journal article
Udgivet:	Nature Publishing Group 2018

Lignende værker

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria
af: David Dulin, et al.
Udgivet: (2018-04-01)

RNA polymerase pausing during initial transcription
af: Duchi, D, et al.
Udgivet: (2016)

Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes
af: Duchi, D, et al.
Udgivet: (2017)

The pause-initiation limit restricts transcription activation in human cells
af: Saskia Gressel, et al.
Udgivet: (2019-08-01)

The elemental mechanism of transcriptional pausing
af: Jason Saba, et al.
Udgivet: (2019-01-01)

Grounded: Transcriptional Pausing in Naive mESCs
af: Guenther, Matthew G., et al.
Udgivet: (2014)

Definition of transcriptional pause elements in fission yeast.
af: Aranda, A, et al.
Udgivet: (1999)

Intermittent Transcription Dynamics for the Rapid Production of Long Transcripts of High Fidelity
af: Martin Depken, et al.
Udgivet: (2013-10-01)

Intermittent Transcription Dynamics for the Rapid Production of Long Transcripts of High Fidelity
af: Martin Depken, et al.
Udgivet: (2013-10-01)

CDK9-dependent RNA polymerase II pausing controls transcription initiation
af: Saskia Gressel, et al.
Udgivet: (2017-10-01)

c-Myc regulates transcriptional pause release
af: Rahl, Peter B., et al.
Udgivet: (2012)

Transcription Pause and Escape in Neurodevelopmental Disorders
af: Kristel N. Eigenhuis, et al.
Udgivet: (2022-05-01)

NKAPL facilitates transcription pause-release and bridges elongation to initiation during meiosis exit
af: Zhenlong Kang, et al.
Udgivet: (2025-01-01)

Single-molecule and super-resolution imaging of transcription in living bacteria
af: Stracy, M, et al.
Udgivet: (2017)

Effects of transcriptional pausing on gene expression dynamics.
af: Tiina Rajala, et al.
Udgivet: (2010-03-01)

Recent advances in understanding σ70-dependent transcription initiation mechanisms
af: Mazumder, A, et al.
Udgivet: (2019)

Transcription pausing regulates mouse embryonic stem cell differentiation
af: Melodi Tastemel, et al.
Udgivet: (2017-12-01)

Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates
af: Ronen Gabizon, et al.
Udgivet: (2018-07-01)

Structures of co-transcriptional RNA capping enzymes on paused transcription complex
af: Yan Li, et al.
Udgivet: (2024-05-01)

Clarifying the Translational Pausing Landscape in Bacteria by Ribosome Profiling
af: Fuad Mohammad, et al.
Udgivet: (2016-02-01)

RNA polymerase II pausing in development: orchestrating transcription
af: Abderhman Abuhashem, et al.
Udgivet: (2022-01-01)

Single-Molecule Studies of Transcription Initiation using a Vesicle Approach
af: Llumigusin, D, et al.
Udgivet: (2012)

A pause site for RNA polymerase II is associated with termination of transcription.
af: Enriquez-Harris, P, et al.
Udgivet: (1991)

c-Myc regulates transcriptional pause release and is a global amplifier of transcription
af: Lin, Charles Yang
Udgivet: (2013)

Translational Control by Ribosome Pausing in Bacteria: How a Non-uniform Pace of Translation Affects Protein Production and Folding
af: Ekaterina Samatova, et al.
Udgivet: (2021-01-01)

Pause
af: Roger Khouri
Udgivet: (2019-09-01)

Beyond the pause
af: Loke, Eden Hui Yi, et al.
Udgivet: (2024)

Concerted transformation of a hyper-paused transcription complex and its reinforcing protein
af: Philipp K. Zuber, et al.
Udgivet: (2024-04-01)

Introduction to pausing and Initiation: Its Terminology and Its Relation to Grammar
af: Ahmad AlOmar
Udgivet: (1977-08-01)

Pauses Reﬂecting the Processing of Syntactic Units in Monolingual Text Production and Translation
af: Sini Immonen, et al.
Udgivet: (2010-10-01)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
af: Gromak, N, et al.
Udgivet: (2006)

Specific transcriptional pausing activates polyadenylation in a coupled in vitro system.
af: Yonaha, M, et al.
Udgivet: (1999)

Role of RNA Polymerase II Promoter-Proximal Pausing in Viral Transcription
af: Marilyn Whelan, et al.
Udgivet: (2022-09-01)

Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting
af: Katjana Tantale, et al.
Udgivet: (2021-07-01)

Transcriptional regulation: effects of promoter proximal pausing on speed, synchrony and reliability.
af: Alistair N Boettiger, et al.
Udgivet: (2011-05-01)

Investigating the role of RNA structures in transcriptional pausing using in vitro assays and in silico analyses
af: Simon Jeanneau, et al.
Udgivet: (2022-12-01)

Pausing for More
af: Sara Wigal, et al.
Udgivet: (2023-09-01)

Series and Pauses: To the Problem of Cutting
af: Smolev Daniil D.
Udgivet: (2024-06-01)

Transcription initiation at a consensus bacterial promoter proceeds via a 'bind-unwind-load-and-lock' mechanism
af: Mazumder, A, et al.
Udgivet: (2021)

The Dance of Pauses in Poetry Declamation
af: Plinio A. Barbosa
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