The use of lithium (alpha-methylbenzyl)allylamide for the asymmetric synthesis of unsaturated beta-amino acid derivatives

The unsaturated β-amino acid derivatives (3R)-(E)-3-(N-tert- butoxycarbonyl)aminohex-4-enoate and methyl (2S,3S)-3-(N-tert- butoxycarbonyl)-amino-2-bydroxyhex-4-enoate have been synthesised from lithium (s)-(α-methylbenzyl)allylamide and (E,E)-tert-butyl hex-2,4- dienoate. After a highly stereoselec...

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Hlavní autoři: Davies, S, Fenwick, DR, Ichihara, O
Médium: Journal article
Jazyk:English
Vydáno: 1997