The use of lithium (alpha-methylbenzyl)allylamide for the asymmetric synthesis of unsaturated beta-amino acid derivatives

The use of lithium (alpha-methylbenzyl)allylamide for the asymmetric synthesis of unsaturated beta-amino acid derivatives

The unsaturated β-amino acid derivatives (3R)-(E)-3-(N-tert- butoxycarbonyl)aminohex-4-enoate and methyl (2S,3S)-3-(N-tert- butoxycarbonyl)-amino-2-bydroxyhex-4-enoate have been synthesised from lithium (s)-(α-methylbenzyl)allylamide and (E,E)-tert-butyl hex-2,4- dienoate. After a highly stereoselec...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Davies, S, Fenwick, DR, Ichihara, O
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	1997

Παρόμοια τεκμήρια

Use of lithium (alpha-methylbenzyl)allylamide for a formal asymmetric synthesis of thienamycin
ανά: Davies, S, κ.ά.
Έκδοση: (1997)

LITHIUM (ALPHA-METHYLBENZYL)ALLYLAMIDE - A DIFFERENTIALLY PROTECTED CHIRAL AMMONIA EQUIVALENT FOR THE ASYMMETRIC-SYNTHESIS OF BETA-AMINO ACIDS AND BETA-LACTAMS
ανά: Davies, S, κ.ά.
Έκδοση: (1995)

Asymmetric synthesis of beta-lactams and pseudopeptides via stereoselective conjugate additions of lithium (alpha-methylbenzyl)-allylamide to alpha,beta-unsaturated iron acyl complexes
ανά: Davies, S, κ.ά.
Έκδοση: (1999)

Selective deprotection strategies to N-(alpha-methylbenzyl)-beta-amino esters and derived beta lactams
ανά: Davies, S, κ.ά.
Έκδοση: (1998)

ASYMMETRIC-SYNTHESIS OF R-BETA-AMINO BUTANOIC ACID AND S-BETA-TYROSINE - HOMOCHIRAL LITHIUM AMIDE EQUIVALENTS FOR MICHAEL ADDITIONS TO ALPHA,BETA-UNSATURATED ESTERS
ανά: Davies, S, κ.ά.
Έκδοση: (1991)

Conjugate addition of lithium N-tert-butyldimethylsilyloxy-N-(alpha-methylbenzyl)amide: asymmetric synthesis of beta(2,2,3)-trisubstituted amino acids
ανά: Bentley, SA, κ.ά.
Έκδοση: (2010)

ASYMMETRIC-SYNTHESIS OF SYN-ALPHA-ALKYL-BETA-AMINO ACIDS
ανά: Davies, S, κ.ά.
Έκδοση: (1994)

ORIGINS OF THE HIGH STEREOSELECTIVITY IN THE CONJUGATE ADDITION OF LITHIUM(ALPHA-METHYLBENZYL)BENZYLAMIDE TO T-BUTYL CINNAMATE
ανά: Costello, J, κ.ά.
Έκδοση: (1994)

Asymmetric synthesis of alpha-amino carbonyl derivatives using lithium (R)-N-benzyl-N-alpha-methylbenzylamide
ανά: Davies, S, κ.ά.
Έκδοση: (2002)

Asymmetric synthesis of N-protected syn and anti (E)-3-amino-2-hydroxy-4-hexenoate: A practical method for the C-alpha epimerization of anti beta-amino-alpha-hydroxy acids
ανά: Brackenridge, I, κ.ά.
Έκδοση: (1999)

Homochiral lithium amides for the asymmetric synthesis of beta-amino acids
ανά: Davies, S, κ.ά.
Έκδοση: (2006)

Doubly diastereoselective conjugate additions of the antipodes of lithium N-benzyl-N-(alpha-methylbenzyl)amide to enantiopure epsilon-O-protected alpha,beta-unsaturated esters derived from D-ribose
ανά: Davies, S, κ.ά.
Έκδοση: (2014)

Conjugate addition to (alpha,beta)(alpha ',beta ')-diendioate esters by lithium (alpha-methylbenzyl)benzylamide: tandem addition-cyclisation versus double addition
ανά: Urones, J, κ.ά.
Έκδοση: (1999)

Continuous Flow Electroselenocyclization of Allylamides and Unsaturated Oximes to Selenofunctionalized Oxazolines and Isoxazolines
ανά: Ohud Alzaidi, κ.ά.
Έκδοση: (2024-03-01)

Asymmetric synthesis of beta-amino-gamma-substituted-gamma-butyrolactones: double diastereoselective conjugate addition of homochiral lithium amides to homochiral alpha,beta-unsaturated esters.
ανά: Cailleau, T, κ.ά.
Έκδοση: (2007)

Asymmetric synthesis of alpha-amino carbonyls (aldehydes, ketones and acids) using lithium (R)-N-benzyl-N-alpha-methylbenzylamide
ανά: Davies, S, κ.ά.
Έκδοση: (2001)

ASYMMETRIC SYNTHESES OF BETA-PHENYLALANINE, ALPHA-METHYL-BETA-PHENYLALANINES AND DERIVATIVES
ανά: Davies, S, κ.ά.
Έκδοση: (1993)

ASYMMETRIC-SYNTHESIS OF ANTI-ALPHA-ALKYL-BETA-AMINO ACIDS
ανά: Davies, S, κ.ά.
Έκδοση: (1994)

ASYMMETRIC-SYNTHESIS OF ANTI-ALPHA-ALKYL-BETA-AMINO CARBOXAMIDES
ανά: Davies, S, κ.ά.
Έκδοση: (1995)

Asymmetric synthesis of alpha-mercapto-beta-amino acid derivatives: application to the synthesis of polysubstituted thiomorpholines
ανά: Candela-Lena, J, κ.ά.
Έκδοση: (2006)

Double asymmetric induction as a mechanistic probe: the doubly diastereoselective conjugate addition of enantiopure lithium amides to enantiopure alpha,beta-unsaturated esters and enantiopure alpha,beta-unsaturated hydroxamates
ανά: Davies, S, κ.ά.
Έκδοση: (2011)

Double asymmetric induction as a mechanistic probe: the doubly diastereoselective conjugate addition of enantiopure lithium amides to enantiopure alpha,beta-unsaturated esters and enantiopure alpha,beta-unsaturated hydroxamates
ανά: Davies, S, κ.ά.
Έκδοση: (2011)

Conjugate addition of lithium N-phenyl-N-(α-methylbenzyl)amide: application to the asymmetric synthesis of (R)-(-)-angustureine.
ανά: Bentley, SA, κ.ά.
Έκδοση: (2011)

Asymmetric synthesis of homochiral Baylis-Hillman products employing (R)-N-methyl-N-alpha-methylbenzyl amide
ανά: Davies, S, κ.ά.
Έκδοση: (2000)

Asymmetric synthesis of a highly functionalized beta-amino acid: the key amino acid of sperabillins B and D
ανά: Davies, S, κ.ά.
Έκδοση: (1999)

Asymmetric synthesis of beta-amino acids via the Michael addition of chiral metal amides
ανά: Davies, S, κ.ά.
Έκδοση: (1997)

The asymmetric synthesis of beta-haloaryl-beta-amino acid derivatives
ανά: Bull, S, κ.ά.
Έκδοση: (2000)

Asymmetric synthesis of beta-pyridyl-beta-amino acid derivatives
ανά: Bull, S, κ.ά.
Έκδοση: (2002)

Asymmetric synthesis of beta-haloaryl beta-amino acid derivatives
ανά: Bull, S, κ.ά.
Έκδοση: (2001)

ASYMMETRIC-SYNTHESIS OF BETA-AMINO-ALPHA-HYDROXY ACIDS VIA DIASTEREOSELECTIVE HYDROXYLATION OF HOMOCHIRAL BETA-AMINO ENOLATES
ανά: Bunnage, M, κ.ά.
Έκδοση: (1994)

AN ASYMMETRIC-SYNTHESIS OF N-PROTECTED BETA-AMINO ALDEHYDES AND BETA-AMINO KETONES
ανά: Davies, S, κ.ά.
Έκδοση: (1995)

Asymmetric synthesis of beta-fluoroaryl-beta-amino acids
ανά: Davies, S, κ.ά.
Έκδοση: (2012)

Asymmetric synthesis of beta-amino acid scaffolds
ανά: Bull, S, κ.ά.
Έκδοση: (2001)

NON-PROTEINOGENIC AMINO-ACID SYNTHESIS - SYNTHESIS OF BETA, GAMMA-UNSATURATED ALPHA-AMINO-ACIDS FROM ASPARTIC-ACID
ανά: Baldwin, J, κ.ά.
Έκδοση: (1989)

Trading N and O: asymmetric syntheses of beta-hydroxy-alpha-amino acids via alpha-hydroxy-beta-amino esters
ανά: Davies, S, κ.ά.
Έκδοση: (2013)

Cyclic beta-amino acid derivatives: synthesis via lithium amide promoted tandem asymmetric conjugate addition-cyclisation reactions.
ανά: Davies, S, κ.ά.
Έκδοση: (2005)

Asymmetric synthesis and applications of beta-amino Weinreb amides: asymmetric synthesis of (S)-coniine.
ανά: Burke, A, κ.ά.
Έκδοση: (2004)

Asymmetric synthesis of syn- and anti-alpha-deuterio-beta(3)-phenylalanine derivatives
ανά: Davies, S, κ.ά.
Έκδοση: (2011)

THE ASYMMETRIC-SYNTHESIS OF BETA-LACTAMS - STEREOCONTROLLED ASYMMETRIC TANDEM MICHAEL ADDITIONS AND ALKYLATIONS OF ALPHA,BETA-UNSATURATED ACYL LIGANDS BOUND TO THE CHIRAL AUXILIARY [BETA-C5H5)FE(CO)(PPH3)]
ανά: Davies, S, κ.ά.
Έκδοση: (1986)

Doubly diastereoselective conjugate additions of the antipodes of lithium N-benzyl-N-(α-methylbenzyl)amide to enantiopure ε-O-protected α,β-unsaturated esters derived from d-ribose
ανά: Davies, S, κ.ά.
Έκδοση: (2014)