Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5.
BACKGROUND: The renal chloride channel ClC-5, which is responsible for Dent's disease, is coexpressed with the vacuolar H+-ATPase in proximal tubules (PT) and alpha-type intercalated cells (IC) of the mature kidney. Neonatal cases of Dent's disease suggest that ClC-5 distribution must be...
Main Authors: | Jouret, F, Igarashi, T, Gofflot, F, Wilson, P, Karet, F, Thakker, R, Devuyst, O |
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Format: | Journal article |
Language: | English |
Published: |
2004
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