Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5.

BACKGROUND: The renal chloride channel ClC-5, which is responsible for Dent's disease, is coexpressed with the vacuolar H+-ATPase in proximal tubules (PT) and alpha-type intercalated cells (IC) of the mature kidney. Neonatal cases of Dent's disease suggest that ClC-5 distribution must be...

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Main Authors: Jouret, F, Igarashi, T, Gofflot, F, Wilson, P, Karet, F, Thakker, R, Devuyst, O
格式: Journal article
語言:English
出版: 2004