Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.
Activation of the complement system results in formation of membrane attack complexes (MACs), pores that disrupt lipid bilayers and lyse bacteria and other pathogens. Here, we present the crystal structure of the first assembly intermediate, C5b6, together with a cryo-electron microscopy reconstruct...
المؤلفون الرئيسيون: | Hadders, M, Bubeck, D, Roversi, P, Hakobyan, S, Forneris, F, Morgan, B, Pangburn, M, Llorca, O, Lea, S, Gros, P |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2012
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مواد مشابهة
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Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9.
حسب: Hadders, M, وآخرون
منشور في: (2012) -
Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9
حسب: Michael A. Hadders, وآخرون
منشور في: (2012-03-01) -
Structural analysis of the soluble C5b-9 complex using cryoelectron microscopy
حسب: Bubeck, D, وآخرون
منشور في: (2007) -
Structure of human complement C8, a precursor to membrane attack
حسب: Bubeck, D, وآخرون
منشور في: (2011) -
Structure of human complement C8, a precursor to membrane attack.
حسب: Bubeck, D, وآخرون
منشور في: (2011)