Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

Εμφάνιση άλλων εκδόσεων (1)

Activation of the complement system results in formation of membrane attack complexes (MACs), pores that disrupt lipid bilayers and lyse bacteria and other pathogens. Here, we present the crystal structure of the first assembly intermediate, C5b6, together with a cryo-electron microscopy reconstruct...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Hadders, M, Bubeck, D, Roversi, P, Hakobyan, S, Forneris, F, Morgan, B, Pangburn, M, Llorca, O, Lea, S, Gros, P
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2012

Παρόμοια τεκμήρια

Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9.
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ανά: Bubeck, D, κ.ά.
Έκδοση: (2007)

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ανά: Grebenik, P, κ.ά.
Έκδοση: (1989)

Single-particle electron microscopy reconstruction of the structure of complement component 8 (C8) at 23 angstrom resolution
ανά: Roversi, P, κ.ά.
Έκδοση: (2008)

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ανά: Nunn, M, κ.ά.
Έκδοση: (2010)

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ανά: Grebenik, P, κ.ά.
Έκδοση: (1992)

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ανά: Caesar, J, κ.ά.
Έκδοση: (2012)

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Erratum to: Inclusive semileptonic b → c ℓ ν ¯ $$ b\to c\ell \overline{\nu} $$ decays to order 1 / m b 5 $$ 1/{m}_b^5 $$
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ανά: Yu Yang, κ.ά.
Έκδοση: (2012-06-01)

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ανά: Korolenkov, Anton Viktorovich, κ.ά.
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ανά: Meri, S, κ.ά.
Έκδοση: (1990)

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ανά: Babizhetskyy V., κ.ά.
Έκδοση: (2006-03-01)

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