A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Protein kinases play a pivotal role in cell signaling, and dysregulation of many kinases has been linked to disease development. A large number of kinase inhibitors are therefore currently under investigation in clinical trials, and so far seven inhibitors have been approved as anti-cancer drugs. In...
| Autors principals: | , , , , , , , , |
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| Format: | Journal article |
| Idioma: | English |
| Publicat: |
2007
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