A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Protein kinases play a pivotal role in cell signaling, and dysregulation of many kinases has been linked to disease development. A large number of kinase inhibitors are therefore currently under investigation in clinical trials, and so far seven inhibitors have been approved as anti-cancer drugs. In...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Fedorov, O, Marsden, B, Pogacic, V, Rellos, P, Müller, S, Bullock, A, Schwaller, J, Sundström, M, Knapp, S
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2007