MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands.

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands.

Toll-like receptors (TLRs) trigger intestinal inflammation when the epithelial barrier is breached by physical trauma or pathogenic microbes. Although it has been shown that TLR-mediated signals are ultimately protective in models of acute intestinal inflammation [such as dextran sulfate sodium (DSS...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Brandl, K, Sun, L, Neppl, C, Siggs, O, Le Gall, S, Tomisato, W, Li, X, Du, X, Maennel, D, Blobel, C, Beutler, B
פורמט: Journal article
שפה:English
יצא לאור: 2010

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