MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands.

Toll-like receptors (TLRs) trigger intestinal inflammation when the epithelial barrier is breached by physical trauma or pathogenic microbes. Although it has been shown that TLR-mediated signals are ultimately protective in models of acute intestinal inflammation [such as dextran sulfate sodium (DSS...

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Príomhchruthaitheoirí: Brandl, K, Sun, L, Neppl, C, Siggs, O, Le Gall, S, Tomisato, W, Li, X, Du, X, Maennel, D, Blobel, C, Beutler, B
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2010