Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility.

Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility.

Rheumatoid arthritis (RA) is an archetypal, common, complex autoimmune disease with both genetic and environmental contributions to disease aetiology. Two novel RA susceptibility loci have been reported from recent genome-wide and candidate gene association studies. We, therefore, investigated the e...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Barton, A, Thomson, W, Ke, X, Eyre, S, Hinks, A, Bowes, J, Gibbons, L, Plant, D, Wilson, A, Marinou, I, Morgan, A, Emery, P, Steer, S, Hocking, L, Reid, D, Wordsworth, P, Harrison, P, Worthington, J
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2008

Những quyển sách tương tự

A re-evaluation of three putative functional single nucleotide polymorphisms in rheumatoid arthritis.
Bằng: Plant, D, et al.
Được phát hành: (2009)

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
Bằng: Barton, A, et al.
Được phát hành: (2008)

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci.
Bằng: McClure, A, et al.
Được phát hành: (2009)

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci (vol 48, pg 1369, 2009)
Bằng: McClure, A, et al.
Được phát hành: (2011)

Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes.
Bằng: Barton, A, et al.
Được phát hành: (2009)

Corrigendum: Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes
Bằng: Barton, A, et al.
Được phát hành: (2010)

Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease.
Bằng: Eyre, S, et al.
Được phát hành: (2010)

Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population.
Bằng: Eyre, S, et al.
Được phát hành: (2010)

Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes (vol 18, pg 2518, 2009)
Bằng: Barton, A, et al.
Được phát hành: (2010)

Whole genome association studies of rheumatoid arthritis and replication of identified susceptibility loci
Bằng: Ke, X, et al.
Được phát hành: (2007)

Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.
Bằng: Orozco, G, et al.
Được phát hành: (2014)

PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.
Bằng: Burr, M, et al.
Được phát hành: (2010)

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.
Bằng: Orozco, G, et al.
Được phát hành: (2011)

Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population.
Bằng: Morgan, A, et al.
Được phát hành: (2009)

No evidence for association of the KLF12 gene with rheumatoid arthritis in a large UK cohort.
Bằng: Eyre, S, et al.
Được phát hành: (2010)

Corrigendum: Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23
Bằng: Orozco, G, et al.
Được phát hành: (2010)

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.
Bằng: Orozco, G, et al.
Được phát hành: (2009)

Rheumatoid arthritis association at 6q23.
Bằng: Thomson, W, et al.
Được phát hành: (2007)

Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study.
Bằng: Orozco, G, et al.
Được phát hành: (2010)

Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.
Bằng: Hinks, A, et al.
Được phát hành: (2010)

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23 (vol 18, pg 2693, 2009)
Bằng: Orozco, G, et al.
Được phát hành: (2010)

Reevaluation of the Interaction Between HLA-DRB1 Shared Epitope Alleles, PTPN22, and Smoking in Determining Susceptibility to Autoantibody-Positive and Autoantibody-Negative Rheumatoid Arthritis in a Large UK Caucasian Population (vol 60, pg 2565, 2009)
Bằng: Morgan, A, et al.
Được phát hành: (2011)

14.5 Rheumatoid Arthritis susceptibility loci; STAT4, TRAF1/C5 and 6q23 region, are also associated with Juvenile Idiopathic Arthritis
Bằng: Hinks A, et al.
Được phát hành: (2008-09-01)

Identification of BACH2 and RAD51B as rheumatoid arthritis susceptibility loci in a meta-analysis of genome-wide data.
Bằng: McAllister, K, et al.
Được phát hành: (2013)

Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs.
Bằng: Eyre, S, et al.
Được phát hành: (2004)

Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.
Bằng: Hinks, A, et al.
Được phát hành: (2012)

Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis.
Bằng: Bowes, J, et al.
Được phát hành: (2010)

Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis
Bằng: Bowes, J, et al.
Được phát hành: (2010)

A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population.
Bằng: Mackie, S, et al.
Được phát hành: (2012)

PREDICTING THE RISK OF RHEUMATOID ARTHRITIS AND ITS AGE OF ONSET: MODELLING GENETIC RISK VARIANTS WITH SMOKING
Bằng: Scott, I, et al.
Được phát hành: (2013)

Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking
Bằng: Scott, I, et al.
Được phát hành: (2013)

Linkage analysis of potential rheumatoid arthritis non-HLA susceptibility loci.
Bằng: MacKay, K, et al.
Được phát hành: (2000)

Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.
Bằng: Hinks, A, et al.
Được phát hành: (2009)

THE HLA CLASS II ASSOCIATIONS OF RHEUMATOID-ARTHRITIS CONFER SEVERITY NOT SUSCEPTIBILITY
Bằng: Gough, A, et al.
Được phát hành: (1992)

A putative resistant DNA marker for wool yellowing susceptibility in sheep
Bằng: M.V. Benavides, et al.
Được phát hành: (2000-06-01)

Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom.
Bằng: MacKay, K, et al.
Được phát hành: (2002)

Functional Annotation of Putative Regulatory Elements at Cancer Susceptibility Loci
Bằng: Stephanie A. Rosse, et al.
Được phát hành: (2014-01-01)

Functional Annotation of Putative Regulatory Elements at Cancer Susceptibility Loci
Bằng: Stephanie A. Rosse, et al.
Được phát hành: (2014-09-01)

Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap
Bằng: Hinks, A, et al.
Được phát hành: (2012)

Epidemiological implications of the susceptibility to BSE of putatively resistant sheep.
Bằng: Kao, R, et al.
Được phát hành: (2003)