Crystal structure of a thwarted mismatch glycosylase DNA repair complex.

Crystal structure of a thwarted mismatch glycosylase DNA repair complex.

The bacterial mismatch-specific uracil-DNA glycosylase (MUG) and eukaryotic thymine-DNA glycosylase (TDG) enzymes form a homologous family of DNA glycosylases that initiate base-excision repair of G:U/T mismatches. Despite low sequence homology, the MUG/TDG enzymes are structurally related to the ur...

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Bibliographic Details
Main Authors:	Barrett, T, Schärer, O, Savva, R, Brown, T, Jiricny, J, Verdine, G, Pearl, L
Format:	Journal article
Language:	English
Published:	1999

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