Crystal structure of a thwarted mismatch glycosylase DNA repair complex.
The bacterial mismatch-specific uracil-DNA glycosylase (MUG) and eukaryotic thymine-DNA glycosylase (TDG) enzymes form a homologous family of DNA glycosylases that initiate base-excision repair of G:U/T mismatches. Despite low sequence homology, the MUG/TDG enzymes are structurally related to the ur...
Autors principals: | Barrett, T, Schärer, O, Savva, R, Brown, T, Jiricny, J, Verdine, G, Pearl, L |
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Format: | Journal article |
Idioma: | English |
Publicat: |
1999
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