Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1.
p38α mitogen-activated protein kinase (p38α) is activated by a variety of mechanisms, including autophosphorylation initiated by TGFβ-activated kinase 1 binding protein 1 (TAB1) during myocardial ischemia and other stresses. Chemical-genetic approaches and coexpression in mammalian, bacterial and ce...
Main Authors: | De Nicola, G, Martin, E, Chaikuad, A, Bassi, R, Clark, J, Martino, L, Verma, S, Sicard, P, Tata, R, Atkinson, R, Knapp, S, Conte, MR, Marber, MS |
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Format: | Journal article |
Language: | English |
Published: |
2013
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